KİŞİSEL BİLGİLER
Adı Soyadı | Dr. Öğr. Üyesi Muhammed Tılahun MUHAMMED |
Birimi | Eczacılık Fakültesi |
Bölüm | Eczacılık Meslek Bilimleri Bölümü |
Ana Bilim Dalı | Farmasötik Kimya Anabilim Dalı |
Telefon | 2462110359 |
E-Posta | E-Posta Adresini Göster |
ORCID ID | 0000-0003-0050-5271 |
Akademik Hesaplar | |
Google Scholar |
Hindex: 11 Alıntı Sayısı: 697 |
Bu sayfadaki kişisel verilerin görünürlüğü KVKK 8. madde hükmü uyarınca ilgili kişinin açık rızası kapsamındadır.
Kişisel verilerinizin görünürlüğünü veya hali hazırdaki verilerinizi Personel Bilgi Sistemi (PBS) ve Akademik Bilgi Sistemi (ABS) üzerinden düzenleyebilirsiniz.
ÖĞRENİM BİLGİLERİ
Lisans | ANKARA ÜNİVERSİTESİ ECZACILIK PR. 10.06.2012 |
Yüksek Lisans | ORTA DOĞU TEKNİK ÜNİVERSİTESİ BİYOMEDİKAL MÜHENDİSLİĞİ (YL) (TEZLİ) 30.12.2015 |
Doktora | ANKARA ÜNİVERSİTESİ TEMEL BİYOTEKNOLOJİ (DR) 13.07.2020 |
İLGİ ALANLARI
YAYINLAR
- Uluslararası Hakemli Dergilerde Yayımlanan Makaleler
- 1 MUHAMMED MUHAMMED TILAHUN, AKI YALÇIN ESİN EMİNE, Computational Insight into the Mechanism of Action of DNA Gyrase Inhibitors; Revealing a New Mechanism. Current Computer-Aided Drug Design, 20(3), , 224-235. Doi: 10.2174/1573409919666230419094700, (2024), (SCI-Expanded)
- 2 MUHAMMED MUHAMMED TILAHUN, AKI-YALÇIN ESİN, Molecular Docking: Principles, Advances, and its Applications in Drug Discovery. Letters in Drug Design & Discovery, 21(3), , 480-495. Doi: 10.2174/1570180819666220922103109, (2024), (SCI-Expanded)
- 3 ERDOĞAN ÜMİT, GÖKÇE EVREN HOMAN, MUHAMMED MUHAMMED TILAHUN, ÖNEM EBRU, ERTEN AYTEN ASENA, SÜLEYMAN OĞLU BUSE, Milk thistle extracts could enhance the UV-protection efficiency and stability of mineral filters in sunscreen formulations. Journal of Photochemistry and Photobiology A: Chemistry Doi: 10.1016/j.jphotochem.2024.115460, (2024), (SCI-Expanded)
- 4 MUHAMMED MUHAMMED TILAHUN, AKSOY NESLİ, KIRILMAZ AYBÜKE, TÜRKMEN ENİSE, Towards Understanding Natural Alpha-Glucosidase Inhibitors: A Computational Study. Ankara Universitesi Eczacilik Fakultesi Dergisi, 48(1), , 205-214. Doi: 10.33483/jfpau.1356028, (2024), (Alan Endeksleri)
- 5 AKKOÇ SENEM, MUHAMMED MUHAMMED TILAHUN, Synthesis, biological application, and computational study of a thymol-based molecule. Journal of Biologically Active Products from Nature, 14(1), , 35-50. Doi: 10.1080/22311866.2024.2318578, (2024), (ESCI: Emerging Sources Citation Index)
- 6 SAEED SADAF, SHAHZADI IRUM, ZAHOOR AMEER FAWAD, AL-MUTAIRI AAMAL A., KAMAL SHAGUFTA, FAISAL SHAH, IRFAN ALI, AL-HUSSAIN SAMİ A., MUHAMMED MUHAMMED TILAHUN, ZAKI MAGDI E.A., Exploring theophylline-1,2,4-triazole tethered N-phenylacetamide derivatives as antimicrobial agents: unraveling mechanisms via structure-activity relationship, in vitro validation, and in silico insights. Frontiers in Chemistry Doi: 10.3389/fchem.2024.1372378, (2024), (SCI-Expanded)
- 7 KIZILYILDIRIM Suna, KANDEMİR Tülay, KENDİR Gülsen, MUHAMMED Muhammed Tılahun, KÖROĞLU Ayşegül, KÖKSAL Fatih, ÖZOĞUL Fatih, The antibacterial effect mechanisms of Laurus nobilis extracts on carbapenem-resistant Acinetobacter baumanii isolates. Food Bioscience , 104011-0. Doi: 10.1016/j.fbio.2024.104011, (2024), (SCI-Expanded)
- 8 Al-Madhagi Haitham, MUHAMMED Muhammed Tılahun, Targeting COVID-19 and varicocele by blocking inflammasome: Ligand-based virtual screening. Archives of Biochemistry and Biophysics , 110107-0. Doi: 10.1016/j.abb.2024.110107, (2024), (SCI-Expanded)
- 9 LAAMARI YASSINE, MUHAMMED MUHAMMED TILAHUN, IRFAN ALI, OUBELLA ALI, ALOSSAIMI MANAL A., GEESI MOHAMMED H., RIADI YASSINE, TAHA MOHAMED LABD, MORJANI HAMID, AUHMANI AZIZ, AIT ITTO MOULAY YOUSSEF, New isoxazoline‐linked 1,3,4‐thiadiazole derivatives: synthesis, antiproliferative activity, molecular docking, molecular dynamics and DFT. Journal of Molecular Structure Doi: 10.1016/j.molstruc.2024.139368, (2024), (SCI-Expanded)
- 10 FAWZI MOURAD, BIMOUSSA ABDOULLAH, LAAMARI YASSINE, MUHAMMED MUHAMMED TILAHUN, IRFAN ALI, OUBELLA ALI, ALOSSAIMI MANAL A., RIADI YASSINE, AUHMANI AZIZ, AIT ITTO MOULAY YOUSSEF, Multitargeted Molecular Docking and Dynamics Simulation Studies of 1,3,4-Thiadiazoles Synthesised from (R)-Carvone against Specific Tumour Protein Markers: An In-silico Study of Two Diastereoisomers. Computational Biology and Chemistry Doi: 10.1016/j.compbiolchem.2024.108159, (2024), (SCI-Expanded)
- 11 KONYAR DİLAN, MUHAMMED MUHAMMED TILAHUN, Investigation of the Inhibitory Potential of Some Antiviral Agents on Human Telomerase by Molecular Docking and Molecular Dynamics Simulation Studies. Ankara Universitesi Eczacilik Fakultesi Dergisi, 48(2), , 576-585. Doi: 10.33483/jfpau.1444259, (2024), (Scopus)
- 12 İNCİ YAREN, KIZILYILDIRIM SUNA, KÖKSAL FATİH, MUHAMMED MUHAMMED TILAHUN, AKKOÇ SENEM, Rifampisin Dirençli Mycobacterium tuberculosis Kompleks Suşları Üzerine Benzimidazolyum Tuzlarının Antimikobakteriyel Etkinliğinin Araştırılması. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 27(1), , 114-119. Doi: 10.18016/ksutarimdoga.vi.1278595, (2024), (ESCI: Emerging Sources Citation Index)
- 13 ERDOĞAN ÜMİT, ERBAŞ SABRİ, MUHAMMED MUHAMMED TILAHUN, ÖNEM EBRU, SOYOCAK AHU, AK AYŞE, Isolation and characterization of thymoquinone from Nigella sativa essential oil: antioxidant and antibacterial activities, molecular modeling studies, and cytotoxic effects on lung cancer A549 cells. Journal of Essential Oil Bearing Plants, 27(3), , 787-803. Doi: 10.1080/0972060X.2024.2352418, (2024), (SCI-Expanded)
- 14 KIZILYILDIRIM Suna, Kandemir Tülay, KENDİR Gülsen, MUHAMMED Muhammed Tılahun, Köroğlu Ayşegül, Ozogul Fatih, Ozogul Fatih, Antibacterial activity of avocado extract (Persea americana Mill.) against aminoglycoside-resistant Klebsiella pneumoniae strains. Food Bioscience , 104523-0. Doi: 10.1016/j.fbio.2024.104523, (2024), (SCI-Expanded)
- 15 SENAN AHMED M., MUHAMMED MUHAMMED TILAHUN, AKKOÇ SENEM, ALHAG SADEQ K., AL-SHAHARI EMAN A., AL-SHURAYIM LAILA A., Modification of ionic liquid and lactoferrin-based small molecules as potential therapeutics against SARS-CoV-2: Molecular docking disclosed the predictable results. Journal of Molecular Structure Doi: 10.1016/j.molstruc.2024.139353, (2024), (SCI-Expanded)
- 16 MUHAMMED Muhammed Tılahun, ER Mustafa, AKKOÇ Senem, Molecular modeling and in vitro antiproliferative activity studies of some imidazole and isoxazole derivatives. Journal of Molecular Structure , 135066-0. Doi: 10.1016/j.molstruc.2023.135066, (2023), (SCI-Expanded)
- 17 Arslan Gülnur, GÖKÇE Başak, MUHAMMED Muhammed Tılahun, Albayrak Özlem, Önkol Tijen, Özçelik Azime Berna, Synthesis, DFT Calculations, and Molecular Docking Study of Acetohydrazide‐Based Sulfonamide Derivatives as Paraoxonase 1 Inhibitors. ChemistrySelect, 8(10), , 0-0. Doi: 10.1002/slct.202204630, (2023), (SCI-Expanded)
- 18 Erzurumlu Yalcin, Aydogdu Esra, Dogan Hatice Kubra, Catakli Deniz, MUHAMMED Muhammed Tılahun, Buyuksandic Buket, 1,25(OH)2 D3 induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells. Cellular Signalling , 110577-0. Doi: 10.1016/j.cellsig.2022.110577, (2023), (SCI-Expanded)
- 19 MUHAMMED MUHAMMED TILAHUN, KÖKBUDAK ZÜLBİYE, AKKOÇ SENEM, Cytotoxic activities of the pyrimidine-based acetamide and isophthalimide derivatives: an in vitro and in silico studies. Molecular Simulation, 49(10), , 982-992. Doi: 10.1080/08927022.2023.2202766, (2023), (SCI-Expanded)
- 20 Erzurumlu Yalcin, Dogan Hatice Kubra, Catakli Deniz, Aydogdu Esra, MUHAMMED Muhammed Tılahun, Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling. Journal of Cell Communication and Signaling, 17(3), , 793-811. Doi: 10.1007/s12079-022-00720-z, (2023), (SCI-Expanded)
- 21 AKKOÇ Senem, Karatas Halis, MUHAMMED Muhammed Tılahun, Kökbudak Zülbiye, Ceylan Ahmet, Almalki Faisal, Laaroussi Hamid, Ben Hadda Taibi, Drug design of new therapeutic agents: molecular docking, molecular dynamics simulation, DFT and POM analyses of new Schiff base ligands and impact of substituents on bioactivity of their potential antifungal pharmacophore site. Journal of Biomolecular Structure and Dynamics, 41(14), , 6695-6708. Doi: 10.1080/07391102.2022.2111360, (2023), (SCI-Expanded)
- 22 Irfan Ali, Zahoor Ameer Fawad, Noor Rida, Rasul Azhar, Al-Hussain Sami A., Zaki Magdi E. A., Faisal Shah, Ahmad Sajjad, MUHAMMED Muhammed Tılahun, BTEAC Catalyzed Ultrasonic-Assisted Synthesis of Bromobenzofuran-Oxadiazoles: Unravelling Anti-HepG-2 Cancer Therapeutic Potential through In Vitro and In Silico Studies. International Journal of Molecular Siciences, 24(3), , 3008-0. Doi: 10.3390/ijms24033008, (2023), (SCI-Expanded)
- 23 ERZURUMLU YALÇIN, MUHAMMED MUHAMMED TILAHUN, Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells. CELLULAR SIGNALLING , 110745-0. Doi: 10.1016/j.cellsig.2023.110745, (2023), (SCI-Expanded)
- 24 IRFAN ALI, FAISAL SHAH, AHMAD SAJJAD, SAIF MUHAMMAD JAWWAD, ZAHOOR AMEER FAWAD, GUL SAMREEN KHAN, JAVID JAMILA, AL-HUSSAIN SAMİ A., MUHAMMED MUHAMMED TILAHUN, ZAKI MAGDI E.A., An Exploration of the Inhibitory Mechanism of Rationally Screened Benzofuran-1,3,4-Oxadiazoles and-1,2,4-Triazoles as Inhibitors of NS5B RdRp Hepatitis C Virus through Pharmacoinformatic Approaches. Biomedicines, 11(11), Doi: 10.3390/biomedicines11113085, (2023), (SCI-Expanded)
- 25 ZAHOOR AMEER FAWAD, SAEED SADAF, RASUL AZHAR, NOREEN RAZIA, IRFAN ALI, AHMAD SAJJAD, FAISAL SHAH, AL-HUSSAIN SAMİ A., SAEED MUHAMMAD ATAR, MUHAMMED MUHAMMED TILAHUN, MUHAMMAD ZEİNAB A., ZAKI MAGDI E.A., Synthesis, Cytotoxic, and Computational Screening of Some Novel Indole–1,2,4-Triazole-Based S-Alkylated N-Aryl Acetamides. Biomediicnes, 11(11), Doi: 10.3390/biomedicines11113078, (2023), (SCI-Expanded)
- 26 Mavvaji Mohammad, MUHAMMED Muhammed Tılahun, AKKOÇ Senem, Synthesis, Cytotoxic Activity, Docking and MD Simulation of N,N‐Disubstituted New Benzimidazolium Salts. ChemistrySelect, 8(43), Doi: 10.1002/slct.202303053, (2023), (SCI-Expanded)
- 27 Ibrahim Bashar Ms, Önem Ebru, Dereli Fatma Tuğçe, Erzurumlu Yalçın, Arin Evren, MUHAMMED Muhammed Tılahun, Anti-Quorum Sensing Activity of Vitis vinifera L. Seed Extract on Some Bacteria: A Greener Alternative Against Antimicrobial Resistance. Erwerbs-Obstbau , 1931-1939. Doi: 10.1007/s10341-022-00783-7, (2023), (SCI-Expanded)
- 28 GÖKÇE BAŞAK, MUHAMMED MUHAMMED TILAHUN, Evaluation of in vitro effect, molecular docking, and molecular dynamics simulations of some dihydropyridine‐class calcium channel blockers on human serum paraoxonase 1 (hPON1) enzyme activity. Biotechnology and Applied Biochemistry, 70(5), , 1707-1719. Doi: 10.1002/bab.2467, (2023), (SCI-Expanded)
- 29 Senan Ahmed M., AKKOÇ Senem, Senan Ahmed M., Al-Areqi Niyazi A.S., MUHAMMED Muhammed Tılahun, Al-Shuraym Laila A., Alhag Sadeq K., AKKOÇ Senem, Synthesis, structure characterization, DFT calculations, and computational anticancer activity investigations of 1-phenyl ethanol derivatives. Journal of Molecular Structure , 136323-0. Doi: 10.1016/j.molstruc.2023.136323, (2023), (SCI-Expanded)
- 30 Akman Soner, AKKOÇ Senem, Zeyrek Celal Tugrul, MUHAMMED Muhammed Tılahun, İlhan İlhan Özer, Density functional modeling, and molecular docking with SARS-CoV-2 spike protein (Wuhan) and omicron S protein (variant) studies of new heterocyclic compounds including a pyrazoline nucleus. Journal of Biomolecular Structure and Dynamics, 41(22), , 12951-12965. Doi: 10.1080/07391102.2023.2169765, (2023), (SCI-Expanded)
- 31 Norouz Dizaji Araz, Yazdani Kohneshahri Matin, Gafil Sena, MUHAMMED Muhammed Tılahun, Ozkan Tulin, Inci Ilyas, Uzun Cengiz , Aki Yalcin Esin, Fluorescence labelled XT5 modified nano-capsules enable highly sensitive myeloma cells detection. Nanotechnology, 33(26), , 0-0. Doi: 10.1088/1361-6528/ac60dc, (2022), (SCI)
- 32 Dereli Fatma Tugce Guragac, Onem Ebru, Arin Evren, Ozaydin Ayse Gul, MUHAMMED Muhammed Tılahun, Persea americana Mill.: As a potent quorum sensing inhibitor of Pseudomonas aeruginosa PAO1 virulence . International Journal of Secondary Metabolite, 9(1), , 14-26. Doi: 10.21448/ijsm.1029610, (2022), (Alan Endeksleri)
- 33 Önem Ebru, KENDİR Gülsen, AKKOÇ Senem, Erzurumlu Yalçın, MUHAMMED Muhammed Tılahun, Özaydın Ayse Gül, Biochemical contents and antiquorum sensing, antiproliferative activities of Opuntia ficus-indica (L.) Mill. Peel extract. South African Journal of Botany , 296-304. Doi: 10.1016/j.sajb.2022.07.024, (2022), (SCI-Expanded)
- 34 MUHAMMED Muhammed Tılahun, Kuyucuklu Gulcan, Kaynak-Onurdag Fatma, Aki-Yalcin Esin, Synthesis, Antimicrobial Activity, and Molecular Modeling Studies of\nSome Benzoxazole Derivatives. Letters in Drug Design & Discovery, 19(8), , 757-768. Doi: 10.2174/1570180819666220408133643, (2022), (SCI-Expanded)
- 35 Farouk Fathima Manaal, Ooi Luyi, Law Christine Shing Wei, Yeong Keng Yoon, Ozturk Ozum, Aki-Yalcin Esin, MUHAMMED Muhammed Tılahun, Synthesis of novel carboxamide- and carbohydrazide-benzimidazoles as selective butyrylcholinesterase inhibitors. Molecular Diversity, 26(5), , 2863-2876. Doi: 10.1007/s11030-022-10476-8, (2022), (SCI-Expanded)
- 36 Muhammed Muhammed Tilahun, Aki-Yalcin Esin, Pharmacophore Modeling in Drug Discovery: Methodology and Current Status. Journal of the Turkish Chemical Society Section A: Chemistry, 8(3), , 749-762. Doi: 10.18596/jotcsa.927426, (2021), (Alan Endeksleri)
- 37 Önem Ebru, Sarisu Hasan Cumhur, Özaydın Ayşe Gül, MUHAMMED Muhammed Tılahun, Ak Ayşe, Phytochemical Profile, Antimicrobial and Anti-Quorum Sensing Properties of Fruit Stalks of Prunus avium L.. Letters in Applied Microbiology, 73(4), , 426-437. Doi: 10.1111/lam.13528, (2021), (SCI-Expanded)
- 38 ÖNEM EBRU, SOYOCAK AHU, MUHAMMED MUHAMMED TILAHUN, AK AYŞE, In vitro and in silico assessment of the potential of Niaouli essential oil as a quorum sensing inhibitor of biofilm formation and its effects on fibroblast cell viability. Brazilian Archives of Biology and Technology Doi: 10.1590/1678-4324-2021200782, (2021), (SCI-Expanded)
- 39 Muhammed Muhammed Tilahun, Son Çağdaş Devrim, İzgü Kadri Fatih, Three dimensional structure prediction of panomycocin, a novel Exo-β-1,3-glucanase isolated from Wickerhamomyces anomalus NCYC 434 and the computational site-directed mutagenesis studies to enhance its thermal stability for therapeutic applications. Computational Biology and Chemistry , 270-277. Doi: 10.1016/j.compbiolchem.2019.04.006, (2019), (SCI)
- 40 Muhammed Muhammed Tilahun, Aki-Yalcin Esin, Homology modeling in drug discovery: Overview, current applications, and future perspectives. Chemical Biology & Drug Design, 93(1), , 12-20. Doi: 10.1111/cbdd.13388, (2019), (SCI-Expanded)
- Kitap
- 1 MUHAMMED MUHAMMED TILAHUN, AKI YALÇIN ESİN EMİNE, Applied Computer-Aided Drug Design: Models and Methods(2023). Bentham Science, Bölüm, (ULUSLARARASI)
VERDİĞİ DERSLER
Araştırma Yöntem Teknikleri
Eczacılığa Giriş ve Terminoloji
Eczacılık Tarihi ve Deontoloji
Farmasötik Kimya I Lab.
Farmasötik Kimya II Lab
Farmasötik Kimya III Lab.
Farmasötik Kimya IV Lab
Medisinal Kimyada Biyoenformatik
Eczacılığa Giriş ve Terminoloji
Eczacılık Tarihi ve Deontoloji
Farmasötik Kimya I Lab.
Farmasötik Kimya II Lab
Farmasötik Kimya III Lab.
Farmasötik Kimya IV Lab
Medisinal Kimyada Biyoenformatik